White Paper: Boosting Lab Performance with Automated Plate Seal Removal


The hands-on removal of a seal from a sample plate is a routine, seemingly undemanding laboratory task. However, removing and/or replacing dozens or hundreds of seals at a time on a repetitive basis can represent a formidable challenge. It’s a challenge facing managers in many high-throughput screening (HTS) and high-content screening (HCS) facilities at pharmaceutical, biotechnology, and academic laboratories worldwide.

Even where a lab invests in automated liquid handlers or storage robotics, this step — unsealing or resealing plates for sample access — often still relies on mistake-prone, tedious, and time-consuming manual labor. Or it may depend on traditional mechanical methods, which present their own difficulties.

Fortunately, adhesive-based de-sealing technology is revolutionizing this lab function. For the first time, automated plate seal removal systems bring the multiple performance advantages of full automation to sample access on microplates and deepwell plates. This report considers the drawbacks of traditional methods, and expands on the benefits of automated seal removers.